L71L (p.Leu71Leu) variant of IRAK4 (Q9NWZ3)
L71L (p.Leu71Leu) in IRAK4 (Q9NWZ3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
L71L (p.Leu71Leu) variant details
- p.Leu71Leu
- rs1940730746
- gnomAD 12-43771271-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.479
- AlphaMissense 0.15
- MetaLR 0.23
- MetaSVM -0.66
- CADD 8.04
- SIFT 0.02
- MutPred 0.48
- Population evidence available
- Structural context available
- Literature evidence available