L59F (p.Leu59Phe) variant of IRAK4 (Q9NWZ3)
L59F (p.Leu59Phe) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L59F (p.Leu59Phe) variant details
- p.Leu59Phe
- gnomAD 12-43771235-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- CADD 22.00
- PolyPhen-2 0.01
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available