K64T (p.Lys64Thr) variant of IRAK4 (Q9NWZ3)
K64T (p.Lys64Thr) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
K64T (p.Lys64Thr) variant details
- p.Lys64Thr
- gnomAD 12-43771249-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- CADD 26.10
- PolyPhen-2 0.86
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available