K41N (p.Lys41Asn) variant of IRAK4 (Q9NWZ3)
K41N (p.Lys41Asn) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
K41N (p.Lys41Asn) variant details
- p.Lys41Asn
- cosmic curated COSV71211
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- CADD 19.30
- PolyPhen-2 0.03
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available