G75V (p.Gly75Val) variant of IRAK4 (Q9NWZ3)
G75V (p.Gly75Val) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
G75V (p.Gly75Val) variant details
- p.Gly75Val
- gnomAD rs899354752
- Missense
- Variant Prioritization Score for Impact Estimate 0.788
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available