G63A (p.Gly63Ala) variant of IRAK4 (Q9NWZ3)
G63A (p.Gly63Ala) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
G63A (p.Gly63Ala) variant details
- p.Gly63Ala
- 1000Genomes rs572719034
- ExAC rs572719034
- gnomAD rs572719034
- Missense
- Variant Prioritization Score for Impact Estimate 0.769
- CADD 24.60
- PolyPhen-2 0.95
- SIFT 0.06
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available