G44V (p.Gly44Val) variant of IRAK4 (Q9NWZ3)
G44V (p.Gly44Val) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
G44V (p.Gly44Val) variant details
- p.Gly44Val
- ExAC rs755265254
- gnomAD rs755265254
- Missense
- Variant Prioritization Score for Impact Estimate 0.783
- CADD 26.50
- PolyPhen-2 0.85
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available