G31V (p.Gly31Val) variant of IRAK4 (Q9NWZ3)
G31V (p.Gly31Val) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
G31V (p.Gly31Val) variant details
- p.Gly31Val
- gnomAD 12-43768203-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.758
- CADD 23.60
- PolyPhen-2 0.68
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available