G31E (p.Gly31Glu) variant of IRAK4 (Q9NWZ3)
G31E (p.Gly31Glu) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G31E (p.Gly31Glu) variant details
- p.Gly31Glu
- gnomAD rs1187447576
- Missense
- Variant Prioritization Score for Impact Estimate 0.743
- CADD 22.70
- PolyPhen-2 0.56
- SIFT 0.84
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available