G17R (p.Gly17Arg) variant of IRAK4 (Q9NWZ3)
G17R (p.Gly17Arg) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- TOPMed rs1332080757
- Missense
- Variant Prioritization Score for Impact Estimate 0.742
- CADD 24.30
- PolyPhen-2 0.28
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available