F72S (p.Phe72Ser) variant of IRAK4 (Q9NWZ3)
F72S (p.Phe72Ser) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
F72S (p.Phe72Ser) variant details
- p.Phe72Ser
- gnomAD 12-43771273-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available