F56I (p.Phe56Ile) variant of IRAK4 (Q9NWZ3)
F56I (p.Phe56Ile) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
F56I (p.Phe56Ile) variant details
- p.Phe56Ile
- gnomAD 12-43771224-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- CADD 23.10
- PolyPhen-2 0.30
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available
- Literature evidence available