F51S (p.Phe51Ser) variant of IRAK4 (Q9NWZ3)
F51S (p.Phe51Ser) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
F51S (p.Phe51Ser) variant details
- p.Phe51Ser
- gnomAD 12-43768263-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.596
- CADD 22.80
- PolyPhen-2 0.02
- SIFT 0.41
- Population evidence available
- Structural context available
- Literature evidence available