D46N (p.Asp46Asn) variant of IRAK4 (Q9NWZ3)
D46N (p.Asp46Asn) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
D46N (p.Asp46Asn) variant details
- p.Asp46Asn
- gnomAD 12-43768247-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- CADD 20.70
- PolyPhen-2 0.00
- SIFT 0.55
- Population evidence available
- Structural context available
- Literature evidence available