D45Y (p.Asp45Tyr) variant of IRAK4 (Q9NWZ3)
D45Y (p.Asp45Tyr) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
D45Y (p.Asp45Tyr) variant details
- p.Asp45Tyr
- gnomAD 12-43768244-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- CADD 26.60
- PolyPhen-2 0.84
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available