D45N (p.Asp45Asn) variant of IRAK4 (Q9NWZ3)
D45N (p.Asp45Asn) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
D45N (p.Asp45Asn) variant details
- p.Asp45Asn
- gnomAD 12-43768244-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.635
- CADD 23.30
- PolyPhen-2 0.10
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available