D45H (p.Asp45His) variant of IRAK4 (Q9NWZ3)
D45H (p.Asp45His) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
D45H (p.Asp45His) variant details
- p.Asp45His
- gnomAD 12-43768244-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.673
- CADD 25.90
- PolyPhen-2 0.78
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available