W25C (p.Trp25Cys) variant of IRAK1 (P51617)
W25C (p.Trp25Cys) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
W25C (p.Trp25Cys) variant details
- p.Trp25Cys
- gnomAD rs1557130990
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.29
- CADD 23.40
- PolyPhen-2 0.89
- SIFT 0.10
- Population evidence available
- Structural context available