T88K (p.Thr88Lys) variant of IRAK1 (P51617)
T88K (p.Thr88Lys) in IRAK1 (P51617) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
T88K (p.Thr88Lys) variant details
- p.Thr88Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.48
- CADD 23.90
- PolyPhen-2 0.66
- SIFT 0.22
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available