S150C (p.Ser150Cys) variant of IRAK1 (P51617)
S150C (p.Ser150Cys) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
S150C (p.Ser150Cys) variant details
- p.Ser150Cys
- Ensembl rs2065761985
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.20
- CADD 18.90
- PolyPhen-2 0.61
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 7.1e-06)
- Structural context available