S140F (p.Ser140Phe) variant of IRAK1 (P51617)
S140F (p.Ser140Phe) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S140F (p.Ser140Phe) variant details
- p.Ser140Phe
- gnomAD rs906604012
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.13
- CADD 24.00
- PolyPhen-2 0.77
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available