S131N (p.Ser131Asn) variant of IRAK1 (P51617)
S131N (p.Ser131Asn) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
S131N (p.Ser131Asn) variant details
- p.Ser131Asn
- gnomAD rs1557130710
- Missense
- Variant Prioritization Score for Impact Estimate 0.083
- REVEL 0.05
- CADD 1.28
- PolyPhen-2 0.01
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available