S120F (p.Ser120Phe) variant of IRAK1 (P51617)
S120F (p.Ser120Phe) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
S120F (p.Ser120Phe) variant details
- p.Ser120Phe
- rs2065707427
- gnomAD X-154012599-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- CADD 9.48
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available
- Literature evidence available