S110L (p.Ser110Leu) variant of IRAK1 (P51617)
S110L (p.Ser110Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
S110L (p.Ser110Leu) variant details
- p.Ser110Leu
- rs192972585
- gnomAD X-154012626-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- CADD 9.33
- SIFT 0.07
- Most common in the 1KG:CHB population (allele frequency 0.0063)
- Structural context available
- Literature evidence available