R94C (p.Arg94Cys) variant of IRAK1 (P51617)
R94C (p.Arg94Cys) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
R94C (p.Arg94Cys) variant details
- p.Arg94Cys
- cosmic curated COSV57653
- TOPMed rs1557130848
- gnomAD rs1557130848
- Missense
- Variant Prioritization Score for Impact Estimate 0.707
- REVEL 0.79
- CADD 27.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3.4e-05)
- Structural context available