R65C (p.Arg65Cys) variant of IRAK1 (P51617)
R65C (p.Arg65Cys) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
R65C (p.Arg65Cys) variant details
- p.Arg65Cys
- cosmic curated COSV10588
- Ensembl rs2065766605
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- REVEL 0.74
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available