R133G (p.Arg133Gly) variant of IRAK1 (P51617)
R133G (p.Arg133Gly) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
R133G (p.Arg133Gly) variant details
- p.Arg133Gly
- TOPMed rs1303739665
- gnomAD rs1303739665
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- REVEL 0.07
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.9e-05)
- Structural context available