R117K (p.Arg117Lys) variant of IRAK1 (P51617)
R117K (p.Arg117Lys) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
R117K (p.Arg117Lys) variant details
- p.Arg117Lys
- gnomAD rs1557130725
- Missense
- Variant Prioritization Score for Impact Estimate 0.0697
- REVEL 0.04
- CADD 5.15
- PolyPhen-2 0.00
- SIFT 0.92
- Most common in the Latino/Admixed American population (allele frequency 3e-05)
- Structural context available