P7L (p.Pro7Leu) variant of IRAK1 (P51617)
P7L (p.Pro7Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P7L (p.Pro7Leu) variant details
- p.Pro7Leu
- cosmic curated COSV57652
- gnomAD rs1557131072
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.18
- CADD 24.60
- PolyPhen-2 0.85
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available