P5T (p.Pro5Thr) variant of IRAK1 (P51617)
P5T (p.Pro5Thr) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P5T (p.Pro5Thr) variant details
- p.Pro5Thr
- gnomAD rs1557131078
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.06
- CADD 21.70
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-06)
- Structural context available