P23S (p.Pro23Ser) variant of IRAK1 (P51617)
P23S (p.Pro23Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P23S (p.Pro23Ser) variant details
- p.Pro23Ser
- gnomAD rs1557130995
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.29
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 5.5e-05)
- Structural context available