P183R (p.Pro183Arg) variant of IRAK1 (P51617)
P183R (p.Pro183Arg) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P183R (p.Pro183Arg) variant details
- p.Pro183Arg
- 1000Genomes rs782031474
- ExAC rs782031474
- TOPMed rs782031474
- gnomAD rs782031474
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.17
- CADD 11.40
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the 1KG:ACB population (allele frequency 0.0072)
- Structural context available