P176A (p.Pro176Ala) variant of IRAK1 (P51617)
P176A (p.Pro176Ala) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P176A (p.Pro176Ala) variant details
- p.Pro176Ala
- ExAC rs782643146
- gnomAD rs782643146
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.09
- CADD 16.40
- PolyPhen-2 0.13
- SIFT 0.12
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00016)
- Structural context available