P174S (p.Pro174Ser) variant of IRAK1 (P51617)
P174S (p.Pro174Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P174S (p.Pro174Ser) variant details
- p.Pro174Ser
- gnomAD rs1557130542
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.04
- CADD 9.54
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available