P171L (p.Pro171Leu) variant of IRAK1 (P51617)
P171L (p.Pro171Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
P171L (p.Pro171Leu) variant details
- p.Pro171Leu
- TOPMed rs1206351667
- gnomAD rs1206351667
- Missense
- Variant Prioritization Score for Impact Estimate 0.072
- REVEL 0.07
- CADD 0.17
- PolyPhen-2 0.00
- SIFT 0.88
- Most common in the Ashkenazi Jewish population (allele frequency 5.3e-05)
- Structural context available