P170L (p.Pro170Leu) variant of IRAK1 (P51617)
P170L (p.Pro170Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
P170L (p.Pro170Leu) variant details
- p.Pro170Leu
- rs1168861199
- gnomAD X-154011838-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- CADD 12.80
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available