P145L (p.Pro145Leu) variant of IRAK1 (P51617)
P145L (p.Pro145Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
P145L (p.Pro145Leu) variant details
- p.Pro145Leu
- rs2065706971
- gnomAD X-154012536-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0853
- CADD 0.63
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 9.3e-05)
- Structural context available
- Literature evidence available