P136S (p.Pro136Ser) variant of IRAK1 (P51617)
P136S (p.Pro136Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P136S (p.Pro136Ser) variant details
- p.Pro136Ser
- TOPMed rs1367337913
- gnomAD rs1367337913
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.10
- CADD 14.20
- PolyPhen-2 0.03
- SIFT 0.41
- Most common in the REMAINING population (allele frequency 4.3e-05)
- Structural context available