P136L (p.Pro136Leu) variant of IRAK1 (P51617)
P136L (p.Pro136Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P136L (p.Pro136Leu) variant details
- p.Pro136Leu
- ExAC rs782689273
- gnomAD rs782689273
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.12
- CADD 1.91
- PolyPhen-2 0.00
- SIFT 0.75
- Most common in the Finnish in Finland (FIN) population (allele frequency 7.5e-05)
- Structural context available