P124L (p.Pro124Leu) variant of IRAK1 (P51617)
P124L (p.Pro124Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
P124L (p.Pro124Leu) variant details
- p.Pro124Leu
- ExAC rs782096938
- TOPMed rs782096938
- gnomAD rs782096938
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- CADD 6.40
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available