P116R (p.Pro116Arg) variant of IRAK1 (P51617)
P116R (p.Pro116Arg) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
P116R (p.Pro116Arg) variant details
- p.Pro116Arg
- ExAC rs782115156
- gnomAD rs782115156
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.11
- CADD 17.60
- PolyPhen-2 0.81
- SIFT 0.15
- Most common in the REMAINING population (allele frequency 4.5e-05)
- Structural context available