P116L (p.Pro116Leu) variant of IRAK1 (P51617)
P116L (p.Pro116Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P116L (p.Pro116Leu) variant details
- p.Pro116Leu
- ExAC rs782115156
- gnomAD rs782115156
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.04
- CADD 12.90
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the South Asian population (allele frequency 0.00037)
- Structural context available