P10H (p.Pro10His) variant of IRAK1 (P51617)
P10H (p.Pro10His) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
P10H (p.Pro10His) variant details
- p.Pro10His
- TOPMed rs1352642683
- gnomAD rs1352642683
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.10
- CADD 22.80
- PolyPhen-2 0.42
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6.6e-05)
- Structural context available