P107L (p.Pro107Leu) variant of IRAK1 (P51617)
P107L (p.Pro107Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P107L (p.Pro107Leu) variant details
- p.Pro107Leu
- TOPMed rs1018128764
- gnomAD rs1018128764
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.09
- CADD 17.10
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 8e-05)
- Structural context available