P104L (p.Pro104Leu) variant of IRAK1 (P51617)
P104L (p.Pro104Leu) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
P104L (p.Pro104Leu) variant details
- p.Pro104Leu
- Ensembl rs1557130761
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.09
- CADD 22.00
- PolyPhen-2 0.11
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available