L158H (p.Leu158His) variant of IRAK1 (P51617)
L158H (p.Leu158His) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L158H (p.Leu158His) variant details
- p.Leu158His
- 1000Genomes rs782766861
- ExAC rs782766861
- gnomAD rs782766861
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.21
- CADD 15.40
- PolyPhen-2 0.71
- SIFT 0.33
- Most common in the 1KG:GWD population (allele frequency 0.0058)
- Structural context available