L108* (p.Leu108Ter) variant of IRAK1 (P51617)
L108* (p.Leu108Ter) in IRAK1 (P51617) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
L108* (p.Leu108Ter) variant details
- p.Leu108Ter
- rs1557127824
- gnomAD X-154012629-A-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.0969
- CADD 2.30
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available