K180T (p.Lys180Thr) variant of IRAK1 (P51617)
K180T (p.Lys180Thr) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
K180T (p.Lys180Thr) variant details
- p.Lys180Thr
- rs782169186
- gnomAD X-154011820-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- CADD 11.70
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available
- Literature evidence available