G63R (p.Gly63Arg) variant of IRAK1 (P51617)
G63R (p.Gly63Arg) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G63R (p.Gly63Arg) variant details
- p.Gly63Arg
- TOPMed rs1557130889
- gnomAD rs1557130889
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.27
- CADD 19.90
- PolyPhen-2 0.08
- SIFT 0.07
- Most common in the South Asian population (allele frequency 9.8e-05)
- Structural context available