G182D (p.Gly182Asp) variant of IRAK1 (P51617)
G182D (p.Gly182Asp) in IRAK1 (P51617) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G182D (p.Gly182Asp) variant details
- p.Gly182Asp
- rs970495832
- Ensembl rs970495832
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.08
- CADD 2.38
- PolyPhen-2 0.01
- SIFT 0.46
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available